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Local, intra-VTA GLP-1R activation appears to align with the latter reports and does not result in any changes in non-goal oriented motor activity (Dickson et al., 1986

Prompt parenteral administration of Vitamin B12 prevents progression of neurologic damage

Side Effects, Tolerability, and Who Should Start With Lower Doses Nausea, vomiting, and constipation occur in 2040% of patients starting GLP-1 therapy, primarily driven by gastric slowdown and altered gut motility